Gene - combatTB X

Rv3835

Type: protein_coding
Name: Rv3835
Locus Name: Rv3835
Product: Conserved membrane protein
Functional Category: None
Location: 4309047..4310396 (+ strand)
Gene Length: 1349 bp
Nucleotides: TGTTGGACGCGCCCGAGCAGGACCCCGTCGATCCCGGCGACCCGGCCAGCCCCCCGCACGGGGAGGCGGAACAGCCGCTGCCCGGGCCTCGGTGGCCACGCGCCCTGCGCGCGTCGGCGACCCGGCGAGCGCTACTCCTCACCGCTTTGGGTGGCCTGCTGATTGCCGGGCTGGTCACCGCGATTCCCGCCGTCGGCCGCGCGCCGGAGCGGCTGGCCGGCTACATCGCCAGCAATCCGGTGCCCAGCACTGGCGCCAAGATCAACGCTTCGTTCAACCGCGTCGCCAGTGGTGACTGCTTGATGTGGCCGGACGGCACGCCGGAGTCTGCCGCCATCGTCAGCTGTGCCGACGAGCACCGGTTCGAAGTCGCCGAGTCCATTGACATGCGGACATTCCCCGGCATGGAGTACGGGCAAAACGCTGCTCCCCCGTCGCCCGCCCGCATTCAGCAGATCAGCGAGGAGCAGTGCGAAGCTGCTGTGCGCCGCTACCTCGGCACGAAGTTCGATCCCAACAGCAAGTTCACCATCAGCATGCTGTGGCCCGGCGACCGGGCGTGGCGGCAGGCCGGTGAGCGCCGCATGCTCTGTGGCTTGCAGTCGCCCGGTCCGAACAACCAGCAGCTCGCCTTCAAGGGCAAGGTCGCCGACATCGACCAGTCCAAGGTCTGGCCGGCCGGTACCTGCCTGGGCATCGATGCCACCACCAACCAGCCGATCGACGTGCCGGTGGACTGCGCGGCACCGCACGCGATGGAGGTATCCGGCACGGTCAACCTGGCCGAGAGGTTTCCCGACGCGCTGCCGAGCGAACCCGAGCAGGACGGGTTCATCAAGGACGCGTGCACCCGGATGACGGACGCCTACCTCGCACCCCTCAAGTTGCGTACCACCACCCTGACGCTGATCTACCCCACGCTGACGCTGCCCAGCTGGTCGGCGGGTAGCCGCGTGGTCGCATGCAGTATCGGCGCGACCCTGGGCAACGGGGGGTGGGCAACCCTGGTGAACAGCGCTAAGGGGGCGCTGCTGATCAACGGCCAGCCGCCGGTACCCCCACCCGACATTCCCGAGGAGCGGCTCAACCTGCCGCCGATTCCGCTTCAGCTGCCAACGCCTCGGCCCGCCCCCCCGGCTCAGCAGCTGCCAAGTACCCCACCAGGCACTCAGCACCTCCCTGCCCAACAGCCAGTGGTTACGCCCACCCGGCCACCCGAATCGCATGCGCCAGCGTCGGCAGCACCGGCCGAGACCCAGCCACCGCCACCAGACGCCGGAGCGCCGCCGGCGACCCAATCACCAGAGGCCACACCGCCTGGCCCCGCCGAGCCCGCACCGGCAGGCTAG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

May play a role in septum formation. {ECO:0000269|PubMed:16735741}.

Family

Unknown

GO

cell wall GO:0005618 cellular_component
extracellular region GO:0005576 cellular_component
plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

IPR026004

UniProt: P9WKW5
GenBank: Rv3835
EnsemblBacteria: Rv3835
Mycobrowser: Rv3835

Summary

Name: Uncharacterized membrane protein Rv3835
Family: Unknown
Protein Sequence: MLDAPEQDPVDPGDPASPPHGEAEQPLPGPRWPRALRASATRRALLLTALGGLLIAGLVTAIPAVGRAPERLAGYIASNPVPSTGAKINASFNRVASGDCLMWPDGTPESAAIVSCADEHRFEVAESIDMRTFPGMEYGQNAAPPSPARIQQISEEQCEAAVRRYLGTKFDPNSKFTISMLWPGDRAWRQAGERRMLCGLQSPGPNNQQLAFKGKVADIDQSKVWPAGTCLGIDATTNQPIDVPVDCAAPHAMEVSGTVNLAERFPDALPSEPEQDGFIKDACTRMTDAYLAPLKLRTTTLTLIYPTLTLPSWSAGSRVVACSIGATLGNGGWATLVNSAKGALLINGQPPVPPPDIPEERLNLPPIPLQLPTPRPAPPAQQLPSTPPGTQHLPAQQPVVTPTRPPESHAPASAAPAETQPPPPDAGAPPATQSPEATPPGPAEPAPAG
Mass: 47,043 Da
Length: 449 Aa

Rv3835 doesn't seem to be a targeted by any drug.

Rv3835 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv.: Proteomics. 2007 May;7(10):1702-18. doi: 10.1002/pmic.200600853.
Identification of cell cycle regulators in Mycobacterium tuberculosis by inhibition of septum formation and global transcriptional analysis.: Microbiology. 2006 Jun;152(Pt 6):1789-97. doi: 10.1099/mic.0.28762-0.
Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling.: Mol Microbiol. 2002 Feb;43(3):717-31.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.