eccD2
- Type
- protein_coding
- Name
- eccD2
- Locus Name
-
Rv3887c
- Product
-
ESX conserved component EccD2. ESX-2 type VII secretion system protein. Probable transmembrane protein.
- Functional Category
-
None
- Location
- 4370155..4371684 (- strand)
- Gene Length
- 1529 bp
- Nucleotides
-
GTGACTGCGCCGCATAAGGTTGCTTTCCCGGCACGTTGTGCGGTCAACATTTGCTACGACAAGCATCTATGCTCCCAGGTATTCCCCGCCGGAATTCCAGTAGAGGGATTCTTCGAAGGAATGGTGGAGTTGTTCGATGCCGATCTGAAGCGCAAAGGTTTCGACGGGGTTGCGCTGCCGGCGGGTAGCTATGAGCTACACAAGATCAACGGGGTGCGGCTGGACATCAACAAGAGCCTCGACGAGCTGGGCGTTCAAGACGGTGACACGCTGGTGCTAGTACCCCGGGTTGCTGGCGAGTCGTTTGAGCCACAGTACGAATCGCTATCCACCGGGCTGGCGGCCATGGGCAAGTGGCTGGGGCGTGACGGCGGGGATCGGATGTTTGCGCCGGTAACCTCGCTGACTGCCGCCCACACCGCCATGGCGATTATCGCCATGGCGGTCGGAGTGGTGCTGGCCCTGACGTTGCGGACACGCACAATCACCGACAGCCCGGTCCCAGCTGCGATGGCTGGCGGGATTGGTGTGCTCCTGGTGATCGGGGCATTGGTGGTGTGGTGGGGTTGGCGGGAGCGCCGTGACCTGTTCAGTGGGTTCGGGTGGCTGGCGGTGGTGTTGCTTGCCGTGGCCGCCGCGTGCGCGCCGCCGGGCGCGCTCGGGGCGGCTCATGCGCTGATCGGGCTCGTGGTGGTGGTTCTGGGTGCGATCACGATCGGCGTGGCGACCCGCAAGCGGTGGCAGACCGCAGTGGTCACCGCGGTGGTAACGGTGTGCGGGATCCTTGCCGCTGTCGCCGCCGTCCGAATGTTTAGGCCGGTTTCGATGCAGGTGCTGGCGATTTGCGTGCTGGTAGGGCTGCTTGTCCTGATCAGGATGACTCCGACCGTTGCGTTGTGGGTGGCACGGGTACGACCCCCGCACTTCGGATCGATCACCGGCCGGGATCTGTTCGCGCGCCGTGCGGGAATGCCCGTCGATACGGTGGCTCCGGTCAGCGAAGCCGACGCCGACGATGAGGACAATGAACTGACCGACATCACCGCCCGCGGCACCGCGATCGCCGCGTCGGCGCGGCTGGTTAACGCGGTACAGGTGGGTATGTGCGTCGGGGTGTCGCTCGTACTGCCCGCCGCGGTATGGGGGGTGCTGACGCCACGTCAACCGTGGGCCTGGTTGGCGTTGTTGGTTGCCGGCTTGACGGTGGGCCTCTTCATCACCCAGGGCCGCGGGTTCGCCGCCAAATACCAAGCGGTCGCATTGGTGTGCGGGGCGTCCGCCGCGGTGTGTGCCGGGGTGCTTAAGTACGCCCTCGACACCCCGAAAGGTGTTCAGACCGGGCTGCTTTGGCCTGCGATCTTCGTCGCGGCTTTCGCCGCATTGGGTTTGGCCGTGGCCCTCGTGGTACCGGCGACGCGGTTTAGGCCGATCATCCGGTTGACCGTGGAATGGCTAGAAGTGCTGGCCATGATCGCGTTGTTACCAGCGGCTGCGGCCCTAGGGGGGCTGTTTGCATGGCTTCGCCACTA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
EccD/Snm4 family
- GO
-
- plasma membrane GO:0005886 cellular_component
- active evasion of host immune response GO:0042783 biological_process
- integral component of membrane GO:0016021 cellular_component
- InterPro
Summary
- Name
- ESX-2 secretion system protein eccD2 (ESX conserved component D2) (Type VII secretion system protein eccD2) (T7SS protein eccD2)
- Family
- EccD/Snm4 family
- Protein Sequence
-
MTAPHKVAFPARCAVNICYDKHLCSQVFPAGIPVEGFFEGMVELFDADLKRKGFDGVALPAGSYELHKINGVRLDINKSLDELGVQDGDTLVLVPRVAGESFEPQYESLSTGLAAMGKWLGRDGGDRMFAPVTSLTAAHTAMAIIAMAVGVVLALTLRTRTITDSPVPAAMAGGIGVLLVIGALVVWWGWRERRDLFSGFGWLAVVLLAVAAACAPPGALGAAHALIGLVVVVLGAITIGVATRKRWQTAVVTAVVTVCGILAAVAAVRMFRPVSMQVLAICVLVGLLVLIRMTPTVALWVARVRPPHFGSITGRDLFARRAGMPVDTVAPVSEADADDEDNELTDITARGTAIAASARLVNAVQVGMCVGVSLVLPAAVWGVLTPRQPWAWLALLVAGLTVGLFITQGRGFAAKYQAVALVCGASAAVCAGVLKYALDTPKGVQTGLLWPAIFVAAFAALGLAVALVVPATRFRPIIRLTVEWLEVLAMIALLPAAAALGGLFAWLRH
- Mass
- 53,278 Da
- Length
- 509 Aa
Rv3887c doesn't seem to be a targeted by any drug.
Rv3887c doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Systematic genetic nomenclature for type VII secretion systems.
- PLoS Pathog. 2009 Oct;5(10):e1000507. doi: 10.1371/journal.ppat.1000507. Epub 2009 Oct 30.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.